Brain Morphometry and Short-Term Stroke Outcome
1
Department of Neurology, Vinnytsia National Pirogov Memorial Medical University, Ukraine
2
Department of Neurology and Neurosurgery of Postgraduate Education Faculty, Vinnytsia National Pirogov Memorial Medical University, Ukraine
3
Department of Psychiatry Addictology and Psychotherapy, Vinnytsia National Pirogov Memorial Medical University, Ukraine
Submission date: 2023-07-31
Final revision date: 2024-01-15
Acceptance date: 2024-04-08
Publication date: 2024-09-03
Corresponding author
Roman Bartiuk
Department of Neurology, Vinnytsia National Pirogov Memorial Medical University, Ukraine
Department of Neurology, Vinnytsia National Pirogov Memorial Medical University, Ukraine
Wiadomości Lekarskie 2024;77(7):1401-1408
KEYWORDS
TOPICS
ABSTRACT
Aim:
The aim of the research was to investigate associations between brain morphometric changes and short-term stroke outcome.
Material and methods:
Materials and methods: in this study, 294 patients with acute stroke were enrolled. All participants underwent magnetic resonance imaging (MRI) and computed tomography (CT) assessment as well as clinical-neurological and cognitive testing.
Results:
Results: in the multivariable regression analysis, bicaudate index (OR = 1.3; 95 % CI 1.1 - 1.7, p=0.018) and ventricular index (OR = 0.7; CI 0.5 - 0.9, p=0.005) were associated with an unfavourable short-term stroke outcome. The univariable regression analysis revealed significant associations between mini-mental state examination scale score (MMSE) and width of the longitudinal cerebral fissure in the anterior part of the frontal lobes (FI) (b -0.8, 95% CI -1.6 – -0.1, p=0.037) as well as width of the cerebral fissure in the area of the skull vault (SW) (b -0.9, 95% CI -1.8 – -0.1, p=0.023). In the multivariable regression model bicaudate index was associated with MMSE score (b coefficient (b) = -1.2; 95 % CI -2.1 – -0.3, p = 0.011).
Conclusions:
Conclusions: our results show that altered brain morphometric indices are associated with unfavourable short-term stroke outcome and cognitive decline.
The aim of the research was to investigate associations between brain morphometric changes and short-term stroke outcome.
Material and methods:
Materials and methods: in this study, 294 patients with acute stroke were enrolled. All participants underwent magnetic resonance imaging (MRI) and computed tomography (CT) assessment as well as clinical-neurological and cognitive testing.
Results:
Results: in the multivariable regression analysis, bicaudate index (OR = 1.3; 95 % CI 1.1 - 1.7, p=0.018) and ventricular index (OR = 0.7; CI 0.5 - 0.9, p=0.005) were associated with an unfavourable short-term stroke outcome. The univariable regression analysis revealed significant associations between mini-mental state examination scale score (MMSE) and width of the longitudinal cerebral fissure in the anterior part of the frontal lobes (FI) (b -0.8, 95% CI -1.6 – -0.1, p=0.037) as well as width of the cerebral fissure in the area of the skull vault (SW) (b -0.9, 95% CI -1.8 – -0.1, p=0.023). In the multivariable regression model bicaudate index was associated with MMSE score (b coefficient (b) = -1.2; 95 % CI -2.1 – -0.3, p = 0.011).
Conclusions:
Conclusions: our results show that altered brain morphometric indices are associated with unfavourable short-term stroke outcome and cognitive decline.
| eISSN: | 2719-342X |
| ISSN: | 0043-5147 |
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