Aim:
Thyroid gland surgery is the standard of care for many thyroid disorders. Two novel surgical instruments have been developed to minimize postoperative problems and optimize hemostatic control during thyroid surgery: ligature precision and harmonic focus. This study aims to evaluate the exact and harmonic focus of ligature with the traditional suture ligation approach with respect to surgical problems, hospital stay, drainage volume, and time spent in the operating room during open thyroidectomy.

Material and methods:
Between February 2018 and March 2020, 180 patients suffering from thyroid disease underwent an open total thyroidectomy at Al-Sader Medical City's general surgery department. These patients were divided into three groups at random: 60 patients were assigned to Group 1 (Ligasure precise) (LS), 60 patients to Group 2 (harmonic FOUCS) (HF), and 60 patients to Group 3 conventional (CAT).

Results:
Regarding age, sex, or histological diagnosis, the three groups did not differ statistically significantly. The mean operative time for the Ligasure (LS) group was 34 minutes, while the Harmonic focus (HF) group was 38 minutes, which was less than that of the Conventional technique (CAT) group. The CAT group had a significantly larger mean drainage volume than the other 2 groups (P<0.001). The three groups' postoperative hypocalcaemia levels did not differ statistically significantly. (p= n.s.). The HF group had a shorter mean hospital stay than the LS group, while the CAT group had the longest hospital stay (P <0.05).

Conclusions:
LigaSure Precise and Harmonic FOUCS are energy-based technologies that are equally safe and efficient when used for vascular dissection.