Vitamin D status as a laboratory marker of whole spectrum of severity of osteoarthritis of knee
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1
Department of internal medicine, College of medicine, University of Thi-Qar, Thi-Qar, 64001, Iraq, Iraq
2
Department of physiology, College of Medicine, University of Thi-Qar, Thi-Qar, 64001, Iraq, Iraq
3
Al-Ghuzi Community physician, University of Warith Al-Anbiyaa, Iraq, Iraq
Submission date: 2024-11-25
Final revision date: 2024-12-22
Acceptance date: 2025-02-10
Publication date: 2025-04-01
Corresponding author
Haider Shahaeed Mohammed
Department of internal medicine, College of medicine, University of Thi-Qar, Thi-Qar, 64001, Iraq, Iraq
Wiadomości Lekarskie 2025;(2):273-280
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ABSTRACT
Aim:
Aims: to pursuit for uncovering any encroachment of vitamin D influence on cardinal prospects of severances of osteoarthritis of knee joint.
Material and methods:
Materials and methods: A specimen of 160 individuals subjected to medical utility in outpatient doctor’s office were enrolled into the evaluations 80 with established determination of osteoarthritis of knee chosen as cases 80 without clinical and radiological proof of knee joint osteoarthritis elected as controls, both were assessed by meticulous clinical and rheumatologic examination, radiological assessment, and vitamin D quantification. The diagnosis of cases was committed in conformity with American college of rheumatology criteria, for whom both pain and radiological severances were gauged.
Results:
Results: mean age is (69.2570), (96) females, 64 males. F:M ratio is 1.5:1, 85 had subnormal vitamin D while 75 had normal vitamin D level. Preponderance who were vitamin D insufficient affiliated to cases 83.5%, while preponderance of those who were vitamin D adequate affiliated to control group with significant association (P-value 0.0001) preponderance of cases who were vitamin D insufficient 60 out of 71 have grade 3 and 4 kellegren-Lawrence score of radiological severity with significant association p-value 0.001, 14 out of 71 and 50 out of 71 case who have vitamin D inadequacy suffering from moderate and severe pain by visual analogue scale successively with significant association P value 0.001.
Conclusions:
Conclusion: vitamin D status had perceptible relevance with assorted facets of severity and perhaps advancement in worsening of knee osteoarthritis, emphasizing the essence of publicizing the vitamin D quantification in those patients.